[If non-stop fatigue in war time is something you want to talk about, Leia is probably one of the galaxy's leading experts. Having that familiarity and knowing full well how to mask it and seem less exhausted than you really are, Leia can guess Anakin is either truly that exhausted or is faking it for sympathy points. She's not sure which would be worse, especially when that implication he's trying to ignore is the main thing she's worried about.

She gives a small, noncommittal shrug at his question, before she sighs, closing her eyes and pursing her lips as she decides just what she wants to say to that. In any other situation, she absolutely would hit him with the Darth Vader comment, knowing what she knows now, but the whole reason she's speaking to him this one time is because she figures she owes it to Padme this once.]

What I mean is, for whatever reason, Padme cared a great deal about you. [something she made sure Leia knew, hence their last fight.]

If you weren't so self-absorbed and intent upon wallowing in your own misery, you would realize she wouldn't want you behaving like this.

[or at least, she assumes. She may not be nice, but it's nicer than calling him a Sith Lord at least. Anakin's mood is the last thing she cares about, and he can mope around all he likes for all she cares, but if there's any risk of Vader, she would rather him cut it out. Which is why she's trying this, hoping it will be like a slap to the face and get him to stop.]